RNA Therapeutics Institute

🧬 New bioRxiv preprint from Watts, Sontheimer and Wolfe labs: Fully Modified SpyCas9 Guide RNAs Enable Robust Genome Editing In Cells and In Vivo https://buff.ly/kKDRVGX

Fully Modified SpyCas9 Guide RNAs Enable Robust Genome Editing In Cells and In Vivo Precision engineering of CRISPR/Cas9 components has advanced genome editing toward therapeutic applications. Completely chemically stabilized guide RNAs (gRNAs) have the potential to improve in vivo editing efficacy while enabling greater flexibility in delivery strategies. However, previous generat...

THANK YOU to all our speakers, panelists, attendees and sponsors for another successful ! Save the dates and join us next year at June 23-25, 2027!!

Translational Discovery session up next! T. Scott Johnson discussing Cross-Species Metabolism & PK of CBP-4888 Including SC & IV Administration in Healthy Individuals