Plant Cell Technology

Moving from solid agar to Temporary Immersion Systems (TIS) is often one of the biggest upgrades a tissue culture lab can make.

But with that shift comes a whole new set of questions:

🔹 How to set up a TIS system in the lab?
🔹 How to assemble and operate a TIS system?
🔹 Where can I get additional components for the TIS system?

That’s exactly why we developed the BioCoupler™ and BioTilt™ systems at Plant Cell Technology—the simplest and most efficient TIS system for tissue culturists.

Instead of dealing with pumps, tangled tubing, and complicated setups, this system simplifies TIS through a passive closed-loop design that is easier to manage and easier to scale.

The science behind it is simple but powerful:
🌱 Intermittent nutrient contact
🌱 Maximum oxygen exposure
🌱 Reduced diffusion limitations compared to solid media

The result?
• Faster multiplication rates
• Stronger, more uniform plantlets
• Better use of your lab space
• Lower contamination risk

Over the past months, we’ve received incredible technical questions from growers and labs using these systems:
🔹 What is the ideal immersion frequency for the BioTilt system?
🔹 How much media is too much?
🔹 How do you transition from manual flipping to automated tilting?
🔹 What causes leakage during flipping?

So, we compiled the most common questions from our community into a practical TIS guide designed to help labs better understand the mechanics behind the BioCoupler+BioTilt System.

Whether you’re experimenting with TIS for the first time or scaling commercial micropropagation, understanding these fundamentals can make a major difference in your results.

Swipe through the guide and let us know:
What’s been your biggest challenge with TIS so far?

And, if you're ready to optimize your lab’s efficiency?

Shop the BioCoupler™ and BioTilt™ system directly at our website: www.plantcelltechnology.com