Cardiology tips updates

In patients undergoing CABG for acute coronary syndrome, routine addition of ticagrelor to aspirin did not improve cardiovascular outcomes compared with aspirin alone and was associated with higher bleeding risk.

Key takeaways:
• Aspirin monotherapy performed similarly
• No ischemic benefit from routine DAPT post-CABG
• Bleeding risk increased with ticagrelor

Clinical context matters: Aspirin remains the foundation after CABG, while DAPT should be reserved for selected high-risk scenarios.

Reference: Jeppsson A, et al. NEJM 2025. DOI:10.1056/NEJMoa2508026