Genetic Engineering & Biotechnology News

AI-Powered Pan-Cancer Map Reveals Tertiary Lymphoid Structures

Researchers at UT MD Anderson Cancer Center say future studies should investigate whether TLS-informed stratification can guide clinical trial design or therapeutic modulation strategies. Led by Linghua Wang, MD, PhD, the team developed scalable artificial intelligence (AI) frameworks to detect, profile and classify TLSs from spatial omics data and routine pathology slides.

The University of Texas at Austin

AI-Powered Pan-Cancer Map Reveals Tertiary Lymphoid Structures Researchers say future studies should investigate whether TLS-informed stratification can guide clinical trial design or therapeutic modulation strategies.

Don't Miss Out! From Sequence to Patient in Under 12 Months: A Case Study in Advancing Complex Cancer Immunotherapies

Broadcast Date: Thursday, June 4, 2026
Time: 10:00 PDT, 13:00 EDT, 17:00 GMT

In this GEN webinar, Joseph Shultz (vice president of technical development and manufacturing, Ottimo Pharma) and Imroz Ghangas (vice president of commercial sales, Asimov) discuss strategies for achieving high-performing clonal titers and advancing a dual-paratopic cancer immunotherapy from sequence to dosed patient in under a year.

Register for this free webinar sponsored by Asimov: https://hubs.li/Q04ggkQw0

Targeting Metabolic Mechanism Restores Chemotherapy Sensitivity in Ovarian Cancer

The data from The Wistar Institute, Temple University, and their collaborators showed elevated levels of the metabolite αKG improved DNA repair, and blocking it made the cancer cells more sensitive to treatment.

Targeting Metabolic Mechanism Restores Chemotherapy Sensitivity in Ovarian Cancer The data showed elevated levels of the metabolite αKG improved DNA repair, and blocking it made the cancer cells more sensitive to treatment.

Biohub Releases Protein Biology World Model to Address Disease

The latest update to the ESM protein language model family has expanded capabilities in binder design and protein function mapping for therapeutic discovery. The release comes just seven months after Biohub recruited the team behind EvolutionaryScale.

Biohub Releases Protein Biology World Model to Address Disease The latest update to the ESM protein language model series supports binder design and protein function mapping for therapeutic discovery.