Borchert Lab

https://thebusinessview.com/borchert-lab-research-at-usa-challenges-longstanding-view-of-gene-regulation/

Borchert lab research at USA challenges longstanding view of gene regulation MOBILE, Ala. – A groundbreaking study from researchers at the Frederick P. Whiddon College of Medicine could redefine how scientists understand the role of DNA in regulating genes. Published in the prestigious peer-reviewed journal Nucleic Acids Research, the study introduces a revolutionary conce...

Borchert Laboratory Awarded $800K NSF Grant.

Dr. Glen Borchert was one of 30 principal investigators invited to a National Science Foundation think tank last summer in Airlie, Virginia. While there, he teamed up with six other investigators with diverse and complementary expertise to study how we communicate with our microbiome. Each member of the group wrote an independent grant covering one aspect of their hypothesis, and Dr. Borchert's research proposal was just awarded $800,000 in funding to examine the role of extracellular RNA (exRNA) in communication between cells and shaping the community of microbes, especially bacteria, that live on and inside humans.

Borchert Lab coauthors paper describing novel lncRNA contributor to SARS-CoV-2 infection:

Immunomodulatory LncRNA on Antisense Strand of ICAM-1 Augments SARS-CoV-2 Infection-associated Airway Mucoinflammatory Phenotype Noncoding RNAs are important regulators of mucoinflammatory response, but little is known about the contribution of airway long noncoding RNAs (lncRNAs) in COVID-19. RNA-seq analysis showed a more than four-fold increased expression of IL-6, ICAM-1, CXCL-8, and SCGB1A1 inflammatory factors; MUC5AC a...