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04/14/2026

We'd like to congratulate grad student Freyja Moser (Muir Lab) who was awarded an NSF GRFP!
Way to go, Freyja!

KEY1 unlocks the pyrenoid 04/08/2026

Congrats to Professor Shan He, whose final postdoctoral project at Princeton was published in Nature Cell Biology last month!
From Dr He: "Biomolecular condensates are non-membrane-bound organelles formed through liquid-liquid phase separation. Despite their importance for biological functions, the mechanisms by which condensate size is actively controlled remain unclear. Using the pyrenoid, a condensate that enhances photosynthetic CO2 fixation in eukaryotic algae, as a model system, we identified a kinase-based mechanism that actively regulates condensate size. Our work establishes a strong foundation for further studies of condensate regulation across a wide range of biological systems."
https://www.nature.com/articles/s41556-026-01908-w

A summary of the work can be found at https://molbio.princeton.edu/news/2026/key1-unlocks-pyrenoid

KEY1 unlocks the pyrenoid “The regulation of condensate assembly and disassembly is a major outstanding question in the field, and this paper is a beautiful elucidation of how that works for the pyrenoid,” says Clifford Brangwynne. Pictured are first authors Shan He and Linnea Lemma.

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