Mouse Specifics Inc.

A ubiquitous neurotransmitter that carries signals between brain cells, dopamine, among its many functions, is involved in multiple aspects of cognitive processing. University of California San Diego researchers recently set out to investigate less understood aspects related to spontaneous impulses of dopamine.

Their results, published July 23 in the journal Current Biology, have shown that mice can willfully manipulate these random dopamine pulses.

'Feel Good' Brain Messenger Dopamine Can Be Willfully Controlled - Neuroscience News Study reveals mice can learn to manipulate random dopamine impulses for reward.

In old mice infected with a SARS-CoV-2–related virus, treatment with senolytics to reduce the senolytic cell burden reduced mortality and increased antiviral antibodies.

Senolytics reduce coronavirus-related mortality in old mice Cellular senescence is a state elicited in response to stress signals and is associated with a damaging secretory phenotype. The number of senescent cells increases with advanced age and this in turn drives age-related diseases. Camell et al. show that senescent cells have an amplified inflammatory....

A UCLA-led study comparing brain cells known as astrocytes in humans and mice found that mouse astrocytes are more resilient to oxidative stress, a damaging imbalance that is a mechanism behind many neurological disorders.

Differences in human, mouse brain cells have important implications for disease research Research brief: Mouse astrocytes, often used in research on human neurological disorders, differ in significant ways from the human version.