Stem Cells Portal

Mesenchymal stem cells (MSCs) had shown great therapeutic potential for tissue damage repair. Moreover, the use of MSCs in liver preservation also shown great therapeutic potential. In this review, we present current literature regarding different strategies for in vitro liver preservation and investigate the potential application of MSCs and derived EVs as an innovative therapeutic tool to precondition grafts before transplantation as well as to prevent ischemia-reperfusion injury.

Mesenchymal Stem Cell Utilization for In Vitro Donor Liver Machine Perfusion Preservation: Current Status and Future Directions Abstract. Liver transplantation is the only effective treatment for end-stage liver disease. Currently, the shortage of high-quality donors has led to the explo

A drug that boosts strength in injured or aging mice restores connections between nerves and muscle and suggests ways to combat weakness in humans due to aging, injury or disease.

Restoring nerve-muscle connections boosts strength of aging mice, Stanford Medicine study finds

Scientists from the UCLA Jonsson Comprehensive Cancer Center have developed a new method to bioprint miniature tumor organoids that are designed to mimic the function and architecture of real tumors. The improved process allows researchers to use an advanced imaging method to study and analyze individual organoids in great detail, which can help researchers identify personalized treatments for people with rare or hard-to-treat cancers.

Improving How Lab-Grown Mini Tumors Predict Cancer Therapy Responses Researchers develop new way to grow and measure how tumor organoids respond to therapy.