Clear Cell Sarcoma Foundation

Researchers are studying several new drugs and combinations in Clear Cell Sarcoma to better understand potential future treatment options. Most of this work is still early and investigational, including preclinical studies and small clinical trials.

Examples include:

Lurbinectedin (being studied for its effects on cancer cell activity)
Selinexor + lurbinectedin (a combination being explored in early research for potential activity)
Targeted therapies such as anlotinib and cabozantinib, which are also under investigation in CCS

👉 What this means: While CCS remains a challenging cancer to treat, researchers are actively exploring multiple approaches. These studies are important early steps in building evidence, but more research is needed to determine which, if any, of these strategies will improve outcomes for patients.

Read more here: https://www.clearcellsarcoma.org/research

CCSF Champions are the heart of our foundation. They are survivors, families, friends, and community members who take action to champion our cause.

Whether it’s fundraising, hosting events, or becoming a recurring donor, every effort makes a difference. These champions are helping turn action into impact and advancing our mission to support those affected by Clear Cell Sarcoma.

One example is Ann Lopez, a CCS survivor who turned her personal journey into purpose after her diagnosis. Today, she serves as CCSF’s Marketing & Communications Director, using her experience to help raise awareness, amplify patient voices, and strengthen outreach across the CCS community.

Learn more here: https://www.clearcellsarcoma.org/get-involved/ccsf-champions

Join a community of advocates, survivors, and supporters making a real difference in the fight against Clear Cell Sarcoma.

To get involved, email: [email protected]

Big things are coming at the Clear Cell Sarcoma Foundation 🎗️

We’re proud to announce the upcoming launch of our CCS AYA (Adolescent & Young Adult) Advocate Team — a new initiative dedicated to empowering young voices within the CCS community.

AYA patients and survivors experience challenges that are unique, complex, and often overlooked. Their stories, perspectives, and leadership are essential in shaping the future of awareness, research, and support for clear cell sarcoma.

This team will create space for:
✨ Advocacy
✨ Storytelling
✨ Connection
✨ Leadership
✨ Community support

We believe the next generation of advocates will help drive meaningful change and bring even greater visibility to this ultra-rare cancer.

Stay tuned — we can’t wait to introduce you to this incredible group. 💛