Biological Seas

Octopuses, like humans, sleep in two stages The trait may have evolved independently twice

Autophagy and autophagy-related pathways in cancer Nature Reviews Molecular Cell Biology

Repetitive elements in aging and neurodegeneration REs comprise approximately half of the genome, with classes of REs including TEs (see Glossary), satellite DNA, rDNA, and segmental duplications [1]. Until recently, REs were mostly ignored due to: (i) their repetitive nature, which complicates sequencing; and (ii) the widespread perception that REs...

Stochasticity explains non-genetic inheritance of lifespan and apparent trade-offs between reproduction and ageing Stochastic effects are central to the biology and demography of ageing. Genetically identical individuals do not all die at the exact same time but show a distribution of lifespan. Although such effects are appreciated, any cascading effects from stochastic effects of ageing are underappreciated. We...