Comprehensive pharmacy review

Drugs affecting the peripheral nervous system PNS are useful for treating conditions including blood pressure disturbances , bronchial asthma, cardiac dysfunctions , anaphylactic reactions , nasal congestion and skeletal muscle spasticity.
Drugs affecting the central nervous system CNS provide anesthesia and sedation, relieve pain and anxiety, suppress movement disorders and epileptic seizures and treat psychotic and affective disorders. These drugs include general and local anesthetics , anxiolytics and sedative hypnotics , opioid analgesics , Antiparkinsonian agents, antiiepileptics, antipsychotics and antidepressants .

Next review is about drugs affecting the nervous system.

Tricyclic amines antidepressants TCAs produce their effect by ?
1)Inhibiting the reuptake of Serotonin.
2)Inhibiting the enzyme which responsible for the breakdown of neurotransmitters in the brain.
3)Inhibiting the reuptake of Serotonin and Norepinephrine.
4)Inhibiting the reuptake of Serotonin , Norepinephrine and Dopamine.
5)Antagoniz alpha- adrenergic and Serotonin receptors.

One wrong statement regarding serotonin and norepinephrine reuptake inhibitors SNRIs ?
1) Serotonin and norepinephrine reuptake inhibitors ( SNRIs) differ from Tricyclic Amines antidepressants in that they have a little activity for alpha adrenergic , cholinergic or histamine receptors.
2) Adverse effects associated with decreasing of diastolic blood pressure .
3) Are inhibitors of the isoenzyme 2D6.
4) SNRIs should not be used with MAOIs owing to risk of serotonin syndrome.
5) Duloxetine is used in the treatment of pain in diabetic neuropathy.