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13/03/2026
Pilot study of a topical magnesium preparation to treat hypomagnesaemia in patients with an ileostomy
Jeremy Nightingale 1 , Ibrahim Al Bakir 2 , Franklin Adaba 1
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PMID: 41648083 PMCID: PMC12851353 DOI: 10.1016/j.intf.2024.100018
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Abstract
Introduction: Patients with a high output ileostomy often have hypomagnesaemia. This study aimed to determine if a magnesium chloride hexahydrate spray would maintain or increase serum magnesium in ileostomy patients with hypomagnesaemia.
Methods: Outpatients with an ileostomy and having chronic hypomagnesaemia (serum magnesium 0.10 mmol/L at week 6, or the avoidance of a planned magnesium infusion. Serum vitamin D and aldosterone levels, and a 24-hour urinary magnesium concentration were measured.
Results: 6 patients completed the study, all had normal vitamin D levels (>45 nmol/L), and 5 of 6 had urinary magnesium concentrations below 0.28 mmol/L. 2 patients had a rise in serum Mg+2 of 0.27 and 0.13 mmol/l respectively and one avoided their planned six-weekly magnesium infusion, No patient had a fall in serum Mg+2 of more than 0.07 mmol/L. Serum and whole cell Mg+2 correlation was linear (r = 0.9181, p < 0.0001). All 6 patients complained of muscle cramping at enrolment; 5 reported an improvement or complete resolution by week 3. Serum aldosterone levels were high at the start in 4 and reduced in 3. Urine magnesium concentration increased in 2.
Conclusions: A topical magnesium chloride hexahydrate spray maintains or improves serum magnesium levels in patients with an ileostomy and hypomagnesaemia and prevents muscle cramps.
27/12/2025
حمِ نفسك وعائلتك من موجة إنفلونزا H1N1
العنوان الفرعي: مع انتشار الفيروس بشكل واسع في لبنان، الوقاية هي الحل.
إرشادات السلامة:
• ضرورة ارتداء الكمامة في الأماكن العامة.
• تجنب الاختلاط المباشر مع كبار السن، الأطفال، والحوامل، حتى في حال عدم ظهور أعراض.
الحل الأمثل: بخاخ الأنف Silvacol من Argilabs
• الوقاية: يقلل من احتمالية الإصابة بالفيروسات المختلفة.
• التعافي: يسرع عملية الشفاء ويعزز جهاز المناعة.
• طريقة الاستخدام: بختان في كل فتحة أنف، ٣ مرات يومياً.
مع Silvacol.. أنت في أمان من فيروسات الرشح والإنفلونزا.
Argilabs 01290796-03202348
healthMagnesium plays a vital role in brain health, nerve communication, and stress regulation. When magnesium levels are low, it can cause poor focus, brain fog, and mental fatigue. Deficiency disrupts energy production and neurotransmitter balance, leading to sluggish thinking, irritability, anxiety, and sleep disturbances—all of which further impair concentration and mood.Magnesium supports testosterone production and balance, particularly in people with low magnesium or those who are physically active. It helps enzymes convert cholesterol into testosterone and reduces SHBG, increasing the amount of free, usable testosterone. Studies show that magnesium supplementation can raise testosterone levels in both sedentary and active individuals, with stronger effects in athletes. Additionally, magnesium's broad role in muscle, nerve, and hormonal functions contributes to overall endocrine health.Magnesium is essential for maintaining a stable heart rhythm by supporting the heart's electrical activity and balancing key electrolytes like potassium and calcium. When magnesium levels drop, it can cause irregular heartbeats or palpitations.Argilabs Magnesium oil, made from magnesium chloride and water, is applied to the skin to deliver magnesium topically. It's often used for localized relief of muscle aches and joint pain, and may help those with digestive issues that limit magnesium absorption.Topical use can sometimes cause mild skin irritation due to fast absorption if you are deficient in magnesium, consistent application daily over several weeks may be needed to notice the effects.Argilalbs 01290796-03202348
ان الاستعمال المنتظم للمغنيسيوم الموضعي عبر الجلد كزيت المغنيسيومً من ارجيلابز هو واحد من أسرع وأفضل الطرق وأكثرها اماناً وتوافرا بيولوجيا لإعادة بناء مخزونً المغنيسيوم لديك بسرعة فيتم تهدئة التشنجات، وموازنة الهرمونات، وإعادة جسمك إلى حيويته ويخفف من الإجهاد وارهاق الحياة الحديثة.
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