Nuclide Notes

☢️ Solid pseudopapillary epithelial neoplasm ☢️ FDG PET/CT shows a well-defined, encapsulated pancreatic tail solid mass measuring approximately 5.9X4.3 cm. The mass exhibits peripheral and internal macrocalcifications with regions of cystic component. Appearance is in favor of SPEN of pancreas, confirmed with biopsy.
🗓 Solid pseudopapillary neoplasm (SPN) of the pancreas is a rare, benign tumor (15% malignant) that predominantly affects young women, typically in their second to fourth decades of life. Characterized by a mix of solid and cystic components, SPNs are often encapsulated and can vary significantly in size. Clinically, patients may present with nonspecific abdominal pain, a palpable mass, or be asymptomatic, with the neoplasm discovered incidentally during imaging for unrelated issues. Diagnostic imaging modalities such as CT scans and MRI can reveal the characteristic features of SPN, including a well-defined mass with solid and cystic areas, hemorrhage, and calcifications. Surgical resection is the treatment of choice and is typically curative.