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Text Based Cosmetic Dosage of Botox and Dysport at Glabellar complex
Faramarz Rafie Researcher Physician,Cosmetic & Aesthetic Dermatology & Laser SurgeryTop Contributor
According to Edited Text Book by Jean and Alastair Carruthers:
Brand Name : Botox Allergan:Vistable 50 U
Women:
Glabella: 20-24 U
Men: 20-40( usually 40-80 U doses were consistently more effective than the 20 u dose)
Dysport or Reloxin(Ipsen):
Glabella:
Women: 50 u
Men: 50 u

Xeomin( Merz)
Women:20 U

Myobloc(Soltice Neuroscience)
Glabella:
Women: 2500 u

Text: Benjamin Ascher ( Informa)
Glabella:
Botox Allergan:
Women: 28 U
Men: Starting Dose 40U into the glabellar complex, with some men needing upwards of 80 U.

Dysport:
Glabella:
Women: 50U
Men: 50U

Rebecca Small (Practical Gide to B.Toxin)

Glabella :
Women: Starting Dose 20 U of OBTX
Men: starting dose 25 U of OBTX

A.Benedetto( B.Toxin in Clinical Dermatology)
Botox:
Glabella:
Women: 25-40 U
Men: 40-80 U

Dysport:
Glabella:
Women: 50U
MEN: 50U

Botox and Sweating is it adrenergic or cholinergic effects?
Faramarz Rafie :Researcher Physician,Cosmetic & Aesthetic Dermatology & Laser SurgeryTop Contributor
Sweating is controlled by the sympathetic nervous system predominantly.There is an exception.Muscarinic receptors on clear cells of eccrine glands are activated by aceylcholine from post ganglionic neurons,stimulating sweat relase, so we can inhibit by Botox effect

Botox: Active Spread or Diffusion?

Faramarz Rafie
Researcher Physician,Cosmetic & Aesthetic Dermatology & Laser Surgery
To me both of them are important.Active Spread has an essential role at botox injection and muscle Relaxation but, it is very dependent on right place of injection. otherwise it may cause alot of side effects.Diffusion has some benefits during an injection, especially when we want to have an diluent injection for the better spread of toxin to the other muscles or the other fibers in a muscle.

the main point is the direction of injection (vertical or transverse),and the depth of injection (Superficial or Deep).on Vertical form such as Procerus muscle injection, all the active spread are inject to the depth of muscle (usually 2- 3 cm).on the other side, when we inject forhead rhytids transversly, the direction of the active spread is linear and normaly the next injection point is 2-3 cm far from the previous point of injection.
it is better to inject the forhead rhytides with a diluent toxin transversly and as a strategy it is better to inject minimal point with minimal dose.It prevents the pteosis and creat a good condition for doing a positive effect of diffusion which covers the other intact parts of frontal muscle.There is less incidence of periostitis during the forhead transvers injection.

The Optimal initial dose for wrinkle reduction in Asians seems to be still lower than that of Caucasians!
Faramarz Rafie
Researcher Physician,Cosmetic & Aesthetic Dermatology & Laser Surgery
1) Interensic ethenic differences in the muscular mass
2) cultural differences: Asian being less facially expressive
3) Widely accepted Mesobotox in South Asia.

This textbook describes medical aesthetics with discussions of skin anatomy and physiology, methods for the treatment of skin aging and rejuvenation, and the most common skin problems and their management. Each topic gives details further with colored images to assist comprehend and appreciate the details. The book discusses diet and foods associated with skin health, skin types, and the most common skin disorders. In particular, for acne and acne rosacea, etiology, management, and treatment are described. It explains how to differentiate between various types of acne. Those who are interested in scientific information on skin-wound healing can find a comprehensive, yet concise and informative, section in this book. The etiology and types of scar formation after injury are also explained.
The book describes the biology of skin aging (including causes of aging like UV radiation and photoaging) and methods for the improvement of premature skin aging (skin care procedures such as laser rejuvenation, medical chemical peels, and the use of antiaging products). Chemical peels, their types, the grades and different acids used, and their protocols are discussed broadly to guide how to perform an effective peel. In addition, microdermabrasion and photo-laser and laser hair reduction are thoroughly discussed in this book. Readers can find complete information on different types of lasers and laser physics. The most appealing areas of medical aesthetics are facial and body countering by derma fillers and Botox injection. This book gives you substantial information about Botox and dermal fillers and the techniques used to perform satisfactory corrective injections. The anatomy and physiology of muscles involved in facial expression are discussed to make you familiar and confident when injecting your patients. For instance, treatment of eyes and forehead wrinkles, frown lines, nasolabial laugh lines, and bunny lines are covered. The most popular facial and body-countering techniques, such as nonsurgical nose jobs; cheek, chin, and lip enhancements; and nonsurgical breast augmentation and lipolysis by mesotherapy, are presented in this book. The book contains other subjects such as client consultation and assessment, laser safety, microbiology and medical infection control for medical aesthetics, and other subjects that make this textbook a reference guide in medical aesthetics for doctors, nurses, and aestheticians.