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Extreme Male Brain Theory is an extension of the Empathizing-Systemizing Theory (E-S).

Extreme male brain theory states that autistic males have higher doses of prenatal testosterone and on average have a more systemizing brain, as opposed to the more empathizing female brain. Baron-Cohen suggests that autistic brains show an exaggeration of the features associated with male brains. These are mainly size and connectivity, with males generally having a larger brain, which is seen in an exaggerated form in those with ASD.

Individuals with ASD were found to have widespread abnormalities in interconnectivity and general functioning in specific brain regions.This could explain the different results on empathy tests between men and women as well as the deficiencies in empathy seen in ASD, as empathy requires several brain regions to be activated which need information from many different areas of the brain.

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Childhood mental and developmental disorders encompass neurodevelopmental, emotional, and behavioral disorders that have broad and serious adverse impacts on psychological and social well-being.

According to the Centers for Disease Control and Prevention, autism spectrum disorder (ASD) is a developmental disability caused by differences in the brain.

ET Health World reported, about 18 million people diagnosed with autism in India and growing rapidly. About 1 to 1.5 per cent of children aged 2-9 years are diagnosed with ASD.

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