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ACE inhibitors produce vasodilation by inhibiting the formation of angiotensin II. This vasoconstrictor is formed by the proteolytic action of renin (released by the kidneys) acting on circulating angiotensinogen to form angiotensin I. Angiotensin I is then converted to angiotensin II by angiotensin converting enzyme. 😊

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Also known as silent hypoxia — meaning, a lack of oxygen in the body’s tissues — the condition occurs when oxygen levels plummet extremely low, yet the patient is still talking and often even walking. This is why it’s considered “silent” or “happy” because the person is unaware of what’s going on.

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