ReadCrystal

Exciting News | Electrolyte Fine-Tuning Alters M*F Catalyst's CO2 Reduction Selectivity, MicroED Reveals M*F Structure

On July 26, 2024, Professor Rong Cao's team from the Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, published an article in Angewandte Chemie International Edition. They synthesized a copper-porphyrin-based metal-organic framework catalyst, FICN-8, and explored its CO2 reduction activity under different electrolyte compositions.

The study found that FICN-8 primarily produced CO in the absence of a proton source, while the main product gradually shifted to formic acid (HCOOH) when a proton source was added to the electrolyte. This discovery provides new insights into altering CO2RR product selectivity by tuning the electrolyte composition.

ReadCrystal Biotechnology collected a total of 11 datasets, from which the four best-quality datasets were selected for combined processing, completing the structure resolution in 4 days.

The full paper is available: https://lnkd.in/gdC9zesF

ReadCrystal specializes in structure determination. For more information, visit the following link: https://lnkd.in/gwwywfG2

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MicroED achieves nearly the same high resolution as X-ray crystallography, but requires single crystal samples only at the nanometer scale. This reduction in sample size greatly decreases the difficulty and time needed for protein single crystal cultivation. For the important co-crystal structure analysis in drug development, MicroED significantly reduces the required crystal size, offering many practical advantages.

For more information, visit the following link: https://www.linkedin.com/pulse/benefits-microed-applications-cocrystal-structure-ckwoc/?trackingId=XQCHoZqFSry2J4Q7ScwRTw%3D%3D

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KRAS protein is an important cancer target protein. ReadCrystal has completed the protein expression and structural analysis of multiple KRAS mutation targets. Based on these experimental conditions and available protein inventory, ReadCrystal has shortened the turnaround time to 1-2 months and ensures the successful delivery of the project.

For more information on the gallery structure of ReadCrystal, please stay tuned! Discover more: https://www.linkedin.com/pulse/gallery-structure-readcrystalkras-readcrystal-technology-oasfc/?trackingId=%2FPVtqx5AWzx85%2FGcDVN2tw%3D%3D

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Delve into the intricate world of drug discovery where structural biology plays a pivotal role. At ReadCrystal, we're committed to advancing drug discovery through a deep understanding of protein structures.

For more information, click here: https://www.linkedin.com/pulse/advancing-drug-discovery-through-structural-biology-r18cc/?trackingId=KbfqntnIREaI19kBP9sAug%3D%3D

Many unknown structures in M*Fs and COFs have been analyzed through MicroED. ReadCrystal specializes in MicroED technology. Our MicroED platform is renowned for its efficiency in rapidly and precisely analyze the structure of nanocrystals and obtain structural information without the need for a long single crystal cultivation process. In addition, MicroED can further test materials such as proteins, peptides, and small drug molecules.

For more information, visit the following link: https://linkedin.com/pulse/structural-analysis-mofs-cofs-through-microed-32t2c/?trackingId=dnn%2F3M9zQ2K8MMaFXe67Kg%3D%3D

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MicroED Technology-Enabled Diffusion Rate Sieving of Propylene and Propane in PCPs Published in "Nature Communications".
ReadCrystal was responsible for the structural analysis work.

For more information, visit the following link: https://linkedin.com/pulse/microed-technology-supports-publication-new-gas-qzpac/?trackingId=1AxlORi6uTDS%2BxAZDhePjA%3D%3D

Great News❗Mastering Chirality with MicroED - the Analysis of Absolute Configuration of Small Molecules

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