RGCC International

📄 New publication from our research team

How long can a cancer cell line be cultured before its gene expression starts to drift, and why does it matter for research?

Our scientists at Central Europe investigated exactly that. By tracking the transcriptomic profile of HCT-116 colon cancer cells over 25 passages (~16 weeks), they found that gene expression remained largely stable up to passage 15. Beyond that point, genes linked to cell proliferation and cell death began to shift - changes that could affect how cells respond to therapies and compromise experimental reproducibility.

The takeaway: passage number is not a minor detail. It's a variable that can fundamentally influence research outcomes.

This work reinforces our commitment to rigorous, reproducible science and to understanding biology at the molecular level.

🔗 Read the full open-access article:

Articles and abstracts - RGCC International Experts in developing and providing personalised cancer genetic tests for doctors and patients, RGCC is a specialist medical genetics company based in Switzerland, with laboratories worldwide.

As Cancer Awareness Month comes to a close, it’s a great time to stay informed and take a closer look at the facts that matter. Learn more about skin , including its different types, stages, and available treatment options, in our patient guide.

📑Read it here: https://rgcc-international.com/patient-information/skin-cancer-treatment

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Treatment of white and black skin cancer | RGCC Our experts explain the latest procedures for treating different skin cancer types and the role of new personalized approaches.

RGCC’s Customer Relationship Manager, Gabriela Kranauer, participated in the “SSAAMP Jahreskongress 2026 – Universum Mensch und Gesundheit,” organized by the Swiss Society for Antiaging and Prevention and held in Zurich, Switzerland on May 16, 2026.

The congress brought together healthcare professionals and industry experts to discuss the latest developments in integrative and preventive medicine. Topics included longevity, long COVID, chronomedicine, and emerging supportive approaches in cancer care.

Events such as SSAAMP provide valuable opportunities to exchange knowledge, explore new scientific perspectives, and stay connected with ongoing advancements in healthcare and patient-centered care.