CIMB MDPI

🍽️🧪 World Food Safety Day Special 🥦✨

What really defines the “health value” of food?

This study looks at phenolic compounds in foods and their antioxidant activity (DPPH assay) — a key indicator of how food components may help neutralize oxidative stress 🍇🫐

🧬 Key focus:
🍷 Phenols as natural antioxidants in food
🧪 DPPH assay for measuring antioxidant capacity
📊 Improved prediction of antioxidant activity across compounds
🥗 Better understanding of functional food properties

💡 Take-home message:
Food safety is not only about contamination — it is also about understanding how food components interact with human health at the molecular level 🧫❤️

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DPPH Measurement for Phenols and Prediction of Antioxidant Activity of Phenolic Compounds in Food Consuming foods with high antioxidant capacity is considered beneficial to health, and predicting the antioxidant capacity of food components is important. In the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, multiple reactions occur simultaneously, and because the experimental conditions are not stan...

🍽️🧬 World Food Safety Day Special ⚖️💊

What if food could quietly influence how cancer treatments work? 🍇🫖

This review explores how dietary components and supplements can modulate key drug transporters involved in chemotherapy response 🧪

🧬 Focus on MDR transporters:
🚪 P-gp
🚪 BCRP
🚪 MRP2

🥦 Key finding:
Natural compounds like flavonoids, curcumin, resveratrol, catechins, and others may alter drug efflux — potentially affecting:
💊 chemotherapy effectiveness
⚖️ drug toxicity balance
🧫 intracellular drug accumulation

💡 Take-home message: diet is not just nutrition — it can interact with therapy outcomes in cancer care 🍽️➡️💊

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Modulation of Multidrug Resistance Transporters by Food Components and Dietary Supplements: Implications for Cancer Therapy Efficacy and Safety The aim of this review is to explore how diet and dietary supplements influence the activity of key multidrug resistance (MDR) transporters—MRP2, BCRP, and P-gp. These transporters play a crucial role in drug efflux from cancer cells and significantly affect chemotherapy outcomes. This review focu...

🌍🦠 World Environment Day Special | Highly Relevant Insight 🌪️✨

Climate change and infectious diseases are increasingly intertwined — shaping a global “perfect storm” for human health 🌡️🌫️

This review on SARS-CoV-2 and environmental change highlights how climate extremes, pollution, and ecological disruption may influence viral transmission, disease severity, and the emergence of new variants 🧬

🌡️ Climate stress → worsened health outcomes
🌫️ Environmental pollution → increased vulnerability
🦠 Viral evolution (e.g., JN.1 variant) → ongoing public health challenge
🌍 Strong call for integrated climate–health strategies

💡 Message of the day: protecting the environment is protecting future pandemic resilience 💚🫁

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SARS-CoV-2 and Environmental Changes: The Perfect Storm The COVID-19 pandemic has had a significant impact on the global economy. It also provided insights into how the looming global climate crisis might be addressed, as there are several similarities between the challenges proposed by COVID-19 and those expected from the coming climate emergency. COVID...

Celebrating Growth: CIMB CiteScore Reaches 5.0! 📈

We are proud to announce that Current Issues in Molecular Biology (CIMB) has seen its CiteScore rise to 5.0. 🌟

This accomplishment is a testament to the high-quality research submitted by our authors and the rigorous work of our reviewers and editors. As an open-access journal, our mission is to disseminate impactful scientific discoveries, and this milestone reinforces our position in the molecular biology community.

A heartfelt thank you to everyone who has contributed to the success of the journal. We look forward to continuing this trajectory and publishing even more influential research in the future! 🧬👏

Visit us : https://brnw.ch/21x35oN

🌍💨 World Environment Day Special 🌿✨

Air pollution doesn’t just affect the planet — it affects us, from skin to heart to lungs 🫁❤️🧴

This preclinical study explores a botanical-based supplement rich in polyphenols 🌿 and its potential to help protect against pollution-induced damage on the cutaneous and cardiopulmonary systems.

🧪 Key focus:
🌫️ Oxidative stress & inflammation caused by air pollution
🫀 Cardiopulmonary health protection
🧴 Skin barrier support against environmental stressors
🌿 Plant-derived bioactive compounds as protective agents

💡 A reminder: protecting the environment also means protecting human health 🌎💚

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Protective Potential of a Botanical-Based Supplement Ingredient against the Impact of Environmental Pollution on Cutaneous and Cardiopulmonary Systems: Preclinical Study Air pollution is a growing threat to human health. Airborne pollution effects on respiratory, cardiovascular and skin health are well-established. The main mechanisms of air-pollution-induced health effects involve oxidative stress and inflammation. The present study evaluates the potential of a pol...

🌟🍎🧬 HIGHLY CITED 2026 🧬🍎🌟

Can a plant-derived extract help protect the liver during cancer treatment? 🏥💊

This study explores apple seed extract (ASE) and its potential to reduce therapy-related liver damage in a cancer model 🐁🫀

⚡ Key insight: dose-dependent effects on apoptosis & survival pathways (PI3K–Akt)
🧪 Suggests partial recovery of liver structure under specific conditions
🎯 Highlights the importance of dosing for translational potential

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Apple Seed Extract in Cancer Treatment: Assessing Its Effects on Liver Damage and Recovery Cancer therapies frequently induce hepatotoxicity, complicating treatment courses and outcomes. Natural products, including polyphenol-rich extracts, have shown hepatoprotective activity via anti-oxidative and anti-inflammatory mechanisms, often linked to NF-κB and PI3K–Akt pathways. Apple-derive...

🌟🧬 HIGHLY CITED 2026 🧬🌟

Could one blood cell population reshape how we monitor autoimmune disease? 🩸⚡

This review highlights plasmablasts as powerful real-time biomarkers of immune activity across diseases like SLE, RA, and vasculitis 🔬🛡️

📊 From cellular dynamics → clinical decision-making
⏱️ Early predictors of relapse after B-cell therapy
🎯 A step toward truly precision immunology

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Plasmablasts as Translational Biomarkers in Autoimmune Diseases: From Cellular Dynamics to Clinical Decision-Making B cells are key drivers of immune dysregulation across systemic autoimmune diseases. Among their progeny, plasmablasts occupy a uniquely revealing niche: short-lived, highly proliferative intermediates that mirror real-time B-cell activation. Their appearance in peripheral blood integrates antigenic...

🌟🦷🔥 HIGHLY VIEWED PAPER ALERT 🔥🦷🌟

Could a natural resin help fight oral infections linked to gum disease? 🌿✨

This highly viewed study explores the effects of Frankincense (Boswellia serrata) extract on key periodontal pathogens 🧫🦠

🔬 Key findings:
🦠 Reduced growth of Porphyromonas gingivalis
🚫 Inhibited biofilm formation (a major driver of chronic infection)
🧬 Decreased intracellular bacterial infection in gingival epithelial cells
⚖️ Selective activity (limited effect on Fusobacterium nucleatum)

💡 Why it matters:
Periodontitis affects a large proportion of the population 😷🦷 and is strongly linked to chronic inflammation. This study highlights the potential of natural plant-derived compounds 🌿 as supportive antimicrobial strategies.

📖 Read the article:

Frankincense (Boswellia serrata) Extract Effects on Growth and Biofilm Formation of Porphyromonas gingivalis, and Its Intracellular Infection in Human Gingival Epithelial Cells Frankincense is produced by Boswellia trees, which can be found throughout the Middle East and parts of Africa and Asia. Boswellia serrata extract has been shown to have anti-cancer, anti-inflammatory, and antimicrobial effects. Periodontitis is an oral chronic inflammatory disease that affects near...

🚨🦠 HIGHLY VIEWED PAPER ALERT 🦠🚨

Can bacteriophages become the next weapon against antibiotic-resistant infections? 💊❌➡️🧬

This highly viewed study introduces a novel Dhillonvirus phage (Ioannina) targeting Escherichia coli with multi-drug resistance 🧫⚔️

🔬 Key highlights:
🧬 Isolation from hospital wastewater treatment input 🚰
🦠 Strong lytic activity against diverse E. coli strains
📊 Broad host range across clinical & environmental isolates
🧫 Whole-genome sequencing (45,270 bp, 61 CDSs)
🔁 Evidence of genetic recombination in tail fiber protein (CDS28)
⚡ Significant divergence from known Dhillonvirus members

💡 Why it matters:
Phage therapy is re-emerging as a promising alternative in the fight against antibiotic resistance 🚑💥

📖 Read the article:

A Novel Dhillonvirus Phage against Escherichia coli Bearing a Unique Gene of Intergeneric Origin Antibiotics resistance is expanding amongst pathogenic bacteria. Phage therapy is a revived concept for targeting bacteria with multiple antibiotics resistances. In the present study, we isolated and characterized a novel phage from hospital treatment plant input, using Escherichia coli (E. coli) as...

🌟🍄 HIGHLY VIEWED PAPER ALERT 🍄🌟

Could a mushroom be part of the future of cancer therapy? 🧬💊

This highly viewed review explores the anticancer potential of Coriolus versicolor (Turkey Tail mushroom) in breast cancer 🩷🎗️

🔬 The authors highlight:
⚡ Antiproliferative effects
💀 Pro-apoptotic & necroptotic activity
🚫 Anti-invasive mechanisms
🛡️ Immunomodulatory properties
🧫 Effects across multiple breast cancer subtypes (including TNBC)

While still in development as an adjunct strategy, the evidence is building toward a fascinating intersection of natural products + oncology 🌿🧪

📖 Read the article:

Exploring the Anticancer Potential of Coriolus versicolor in Breast Cancer: A Review Breast cancer remains a leading cause of morbidity and mortality among women globally, with increasing incidence projected in the coming years. Despite advances in standard oncologic therapies, there is a growing interest in supportive interventions that enhance treatment efficacy and reduce adverse...