Trempe Lab

A bit late, but congratulations to our own Shafqat Rasool for winning a well-deserved CRBS scholarship.

Very interesting paper, for a tool I’m using quite a fair bit.

Evaluating drug targets through human loss-of-function genetic variation Analysis of predicted loss-of-function variants from 125,748 human exomes and 15,708 whole genomes in the Genome Aggregation Database (gnomAD) provides a roadmap for human ‘knockout’ studies and a guide for future research into disease biology and drug-target selection.

Amazing... may help in designing neutralizing antibodies.

Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2 Scientists are racing to learn the secrets of severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2), which is the cause of the pandemic disease COVID-19. The first step in viral entry is the binding of the viral trimeric spike protein to the human receptor angiotensin-converting enzyme 2 (A...

Y a t’il un ingénieur dans la salle?

Code Life Ventilator Challenge To design a low-cost, simple, easy-to-use and easy-to-build ventilator that can serve the COVID patients, in an emergency timeframe.