Cordat Lab

Cordat Lab

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Urinary sodium wasting and disrupted collecting duct function in mice with distal renal tubular acidosis mutations 10/01/2025

Here is our newest publication! Congratulations to first author Priyanka Mungara and all authors:

Urinary sodium wasting and disrupted collecting duct function in mice with distal renal tubular acidosis mutations Summary: Mouse lines carrying Ae1 L919X or R607H knock-in variations that mimic human distal renal tubular acidosis (dRTA) display urinary sodium waste, as seen in some patients with dRTA, and upregulation of tight junction proteins claudin 4 and 10b, when exposed to a salt-depleted acid challenge.

Photos from Cordat Lab's post 04/08/2024

Priyanka and Grace had a great time at the American Physiological Society Meeting in Long Beach California last week!

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