Oroboros Instruments

On World Brain Tumor Day, we emphasize the growing importance of metabolism and mitochondrial research in advancing our understanding and treatment of brain tumors.
Martell et al. used high-resolution respirometry to characterize glioblastoma cells with a mitochondrial metabolic phenotype. Patient samples following temozolomide and radiation therapy showed increased respiratory activity, revealing a potential metabolic vulnerability that could be therapeutically targeted.
Studies like this deepen our understanding of how metabolic rewiring and mitochondrial function shape brain tumor progression and open new avenues for targeted therapies.
Read 📖: https://buff.ly/9Ovnovr

Author affiliations:
Rady Faculty of Health Sciences, University of Manitoba
University of Manitoba: Faculty of Science
CancerCare Manitoba Research
McMaster University
Texas Children's
Baylor College of Medicine

Funding:
Canadian Institutes of Health Research
Canadian Cancer Society
Société de recherche sur le cancer / Cancer Research Society
Health Sciences Centre Foundation

We’re looking forward to attending next week!

Elettra Leo will present:
“Mitochondrial Ca2+ uptake is constrained in an exercise-mimicking model of functional hypoxia” https://buff.ly/OuNt25z

🗓 Monday, June 1
⏰ 01:15–02:30 pm
📍 Session 6: Hot Topic: GLP1 agonists, Skeletal Muscle and Exercise
🪧 Poster #5024

If you’re attending, stop by the poster and say hello — we’d love to chat about the work.