TriCan Health

Earlier this month, TriCan Health presented at the Pancreas Club meeting in Chicago. It was a great opportunity for pancreas surgeons and others in attendance to get access to a free platform to find best-match clinical trials for patients.

Many thanks to the Nikki Mitchell Foundation for the opportunity!

I had three key takeaways from the meeting:

1. RAS Inhibitors show incredible promise. The physicians in the audience were keenly focused on daraxonrasib and other drugs currently in trials (note - there are 42 (!) different trials in the US targeting RAS recruiting right now)

2. Personalization is king. Companies like Tempus AI provide genomic reports on the mutational burden within each tumor - so not just a binary measure of whether or not a biomarker is present, but to what extent. One pathologist presented research showing that two different tumors from a *single* origin site, metastasized in the *same* organ, might behave differently and therefore might benefit from individualized treatment. So not just personalized medicine per patient - personalized medicine *per tumor*. Amazing.

3. Organoids may help pinpoint effective therapies. An MD PhD at the meeting shared that cells taken from a tumor can be grown to ~1,000-cell organoids within about a week, and then those organoids can be used to select specific therapies, thereby avoiding resistance to typical standard of care adjuvant/neoadjuvant chemotherapies.

Incredible science continues to be conducted to address pancreatic cancer - many thanks to all the researchers and clinicians working every day to improve lives!

Episode #5 of Clinical Trials Explained, hosted by Sky Foundation, Inc. and TriCan Health, is taking place tomorrow, Wednesday the 22nd at noon EDT! Register here: 2a3e164c-8aca-48ad-95c3-2573bfedb6cc@a54392ec-492c-4907-95fe-e7eb2191a6e1" rel="ugc" target="_blank">https://events.teams.microsoft.com/event/2a3e164c-8aca-48ad-95c3-2573bfedb6cc@a54392ec-492c-4907-95fe-e7eb2191a6e1

Two long-time pancreatic cancer survivors will share their stories and how they approached clinical trials as a critical part of their informed decision for treatment options. Please register and join this free session!

Register here (50cc191a-03c7-46a8-893f-4fd2842abb81@a54392ec-492c-4907-95fe-e7eb2191a6e1?blm_aid=11688960)" rel="ugc" target="_blank">https://events.teams.microsoft.com/event/50cc191a-03c7-46a8-893f-4fd2842abb81@a54392ec-492c-4907-95fe-e7eb2191a6e1?blm_aid=11688960) for free webinar Episode #4 of the series Pancreatic Cancer Clinical Trials Explained, titled

Discovery & Enrollment

This session provides a practical, step-by-step guide for patients and caregivers navigating the clinical trial process, presented by Dr. Philip, Chair of Hematology/Oncology at Henry Ford Cancer Institute, and Laura Wood, RN, MSN, OCN at University of Michigan Cancer Center.

You’ll learn:

- What questions to ask your oncologist about clinical trials
- How eligibility criteria really works
- What documents and medical records you should have ready
- What to expect during screening and enrollment
- Why promising drugs cannot be offered outside of clinical trials
- How to prepare for conversations with trial site

Who should attend? Patients, caregivers, and family members actively exploring clinical trials or preparing for enrollment.

Register here for a webinar hosted by Sky Foundation Inc. and TriCan Health on finding pancreatic cancer clinical trials. (e55ac7bd-1e2d-464e-ab2a-2c4e5bb14cab@a54392ec-492c-4907-95fe-e7eb2191a6e1?blm_aid=11688960)" rel="ugc" target="_blank">https://events.teams.microsoft.com/event/e55ac7bd-1e2d-464e-ab2a-2c4e5bb14cab@a54392ec-492c-4907-95fe-e7eb2191a6e1?blm_aid=11688960)

This is Episode #3 in the series, focused on finding trials in Michigan (where Sky Foundation operates), designed to help patients and caregivers demystify clinical trials and receive practical advice on how to consider trials as treatment options.

Please join!

Excellent resource for patients and caregivers battling pancreatic cancer. The Seena Magowitz Pancreatic Cancer Foundation is terrific, as is Steven Merlin, who's moderating the session.

13-Year pancreatic cancer survivor Steven Merlin hosts the Pancreatic Cancer Support for Survivorship Support Group Meeting on March 17th at 5:30pm Eastern time. Please join this live zoom meeting and speak directly with Steven Merlin, share information, and have your questions answered.

https://seenamagowitzfoundation.org/meeting/survivors-zoom-meeting-on-march-17th/

Register today for a webinar this Wednesday 18 February at 12noon ET to help navigate pancreatic cancer and find clinical trials. Hosted by Sky Foundation, Inc. and TriCan Health, we'll be speaking with two leading doctors from Karmanos Cancer Institute in Detroit, MI.

5f3ca3b9-4948-422c-9313-2f6f28f7396c@a54392ec-492c-4907-95fe-e7eb2191a6e1" rel="ugc" target="_blank">https://events.teams.microsoft.com/event/5f3ca3b9-4948-422c-9313-2f6f28f7396c@a54392ec-492c-4907-95fe-e7eb2191a6e1