BioMat4CAST

We’re proud to share that our latest review article has been selected as a cover feature in Small Structures.
It’s an honor to see our work highlighted in this way, and we’re grateful to the journal for this recognition.

🧬New Research Out Now in PLOS ONE!

𝐇𝐨𝐰 𝐝𝐨𝐞𝐬 𝐨𝐮𝐫 𝐢𝐦𝐦𝐮𝐧𝐞 𝐬𝐲𝐬𝐭𝐞𝐦 𝐚𝐜𝐭𝐮𝐚𝐥𝐥𝐲 𝐝𝐞𝐬𝐭𝐫𝐨𝐲 𝐢𝐧𝐯𝐚𝐝𝐢𝐧𝐠 𝐦𝐢𝐜𝐫𝐨𝐛𝐞𝐬?
Our new paper investigates the chemistry of hypohalous acids produced by mammalian peroxidases. Because these species are highly unstable and not experimentally accessible in purified form, we used DFT calculations to quantify their dissociation energetics. The results support preferential formation of atomic oxygen (ATOX), a highly reactive oxidant, rather than cationic halides, providing additional context for the antimicrobial efficacy of lactoperoxidase, eosinophil peroxidase, and myeloperoxidase systems.
📄 𝐑𝐞𝐚𝐝 𝐭𝐡𝐞 𝐟𝐮𝐥𝐥 𝐨𝐩𝐞𝐧-𝐚𝐜𝐜𝐞𝐬𝐬 𝐚𝐫𝐭𝐢𝐜𝐥𝐞:
🔗https://doi.org/10.1371/journal.pone.0339356