STRAY AID Initiative

Grateful for the kindness that filled our Baybay dogs’ bowls today. Thank you for supporting and caring for them 💕🐾
ULAM: Sir Marlon Teraytay Andrino
RICE: Di Gi
DOG FOOD: Di Gi

In the wake of recent disasters and calamities, such as fires and earthquakes, pet owners in Cebu province are urged to unchain or not to keep their pets inside cages.

Read story here: https://l.cdn.ph/7Yc8jh

Rabies
( source: The 5-Minute Clinical Consult 2023)



Rabies is a nearly universally fatal viral encephalitis caused by a neurotropic RNA virus (genus Lyssavirus) transmitted via saliva of infected animals, most commonly through bites or scratches .



Initial symptoms are nonspecific: fever, malaise, headache, and paresthesias near the bite site. As it progresses:
• Neurologic phase: agitation, hydrophobia, aerophobia, confusion, seizures, coma
• Paralytic form: ascending flaccid paralysis



Diagnosis is mainly clinical but supported by:
• RT-PCR or immunofluorescence on saliva, corneal smears, or nape-of-neck skin biopsy
• Antibody titers in serum or CSF
• MRI/CT: nonspecific or normal in early stages
• Negri bodies (postmortem) in Ammon horn or cerebellar Purkinje cells 

Diagnosis

Includes rapidly progressive encephalitis and neuromuscular conditions:
• HSV, Japanese encephalitis, West Nile virus
• Botulism, tetanus
• Guillain-Barré syndrome
• Substance intoxication 


• Postexposure prophylaxis (PEP) is effective before symptom onset:
• Wound cleansing with soap and virucidal agents
• Rabies immune globulin (RIG)
• Rabies vaccine (HDCV or PCEC) on days 0, 3, 7, 14, and 28 
• Preexposure vaccination for high-risk individuals
• After symptom onset: treatment is palliative
• Experimental protocols (e.g., Milwaukee protocol) have very limited success 

-Up & Prognosis
• Fatality rate approaches 100% once symptoms appear
• Less than 20 documented survivors—most received some form of immunization
• Survivors may have long-term neurologic impairments
• Animal testing via direct fluorescent antibody on brain tissue is important post-exposure